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KMID : 0362420110490040300
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Journal of Korean Academy of Prosthodontics
2011 Volume.49 No. 4 p.300 ~ p.307
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The effect of PostGraftTM on implants were installed at the tibia of ovariectomized rats
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Zhao Chun-Ri
Kim Se-Won
Choi Yu-Sung
Cho In-Ho
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Abstract
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Purpose: This study evaluated PostGraftTM which enhances implant stability and bone density.
Materials and Methods : Forty eight implants were installed at the tibia of ovariectomized rats. The group administrated with PostGraftTM was the experimental group, and the control group was not administrated. Implant stability was evaluated at the 2nd, 4th and 6th week by Periotest value, bone mineral density, bone-to-implant contact. These values were analyzed statistically with Mann-Whitney U test (P<.05). Histological analysis was evaluated at the 2nd, 4th and 6th week.
Results: According to the Periotest(R). measurement, both experimental and control groups showed decrease in values as time elapsed. Greater decrease was observed in the experimental group but there was no significant difference. By examining the radiographic images, both experimental and control groups showed tendency of increase in bone density. Greater increase was seen in the experimental group but there was no significant difference. According to the bone-to-implant contact measurement, both experimental and control groups showed increase in values as time elapsed. Greater increase was seen in the experimental group. At the 2nd and 4th week, there was no significant difference. But at the 6th week, there was significant difference (P<.05). By histological analysis, both experimental and control groups showed ncrease in bone formation as time elapsed. In addition, greater increase was seen in the experimental group.
Conclusion:. It could be concluded that the PostGraftTM medicated group showed better results in the bone density and osseointegration.
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KEYWORD
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PostGraftTM Implant stability, Periotest value, Bone-to-implant contact, Bone density
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